Thermo Fisher Scientific GPCR GPR120 Polyclonal Antibody, FITC
GPCR GPR120 단백질을 인식하는 FITC 결합 폴리클로날 항체로, Western blot, ELISA, IP 등 다양한 응용에 적합합니다. 사람, 마우스, 랫트에 반응하며 친화 크로마토그래피로 정제되었습니다. 형광 검출용으로 연구 전용입니다.
- 카탈로그번호
- FFAR4-1-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | N-epitope synthetic peptide within amino acid region 1–80 on human FFAR4 (GPR120) protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
An EST for GPR120 has been isolated from a human colon cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms. Various activating ligands induce conformational changes in GPCRs, leading to signaling via G-proteins and downstream effectors. Studies have also demonstrated mechanisms of negative regulation of GPCRs, which are critical for cellular physiology and pharmacological research. GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) exemplify the therapeutic importance of this receptor family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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