Thermo Fisher Scientific H3K14me3 Polyclonal Antibody
H3K14me3에 특이적인 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 반응성. Affinity chromatography로 정제된 액상형 제품이며, -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys14. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815934 |
Product Specific Information
This antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys14.
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. Together with other core histone proteins, it forms the nucleosome structure by binding to DNA. Histones play a central role in transcription regulation, DNA repair, replication, and chromosomal stability. Post-translational modifications of histones, such as methylation, acetylation, and phosphorylation, influence chromatin structure and gene expression by altering DNA accessibility or recruiting transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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