Thermo Fisher Scientific EHD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human EHD2 (NP_0554162) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EHD2,uniProtId:Q9NZN4-1,ncbiNodeId:9606,antigenRange:244-543,antigenLength:543,antigenImageFileName:PA5-116554_EHD2_Q9NZN4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116554_EHD2_Q9NZN4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901185

Product Specific Information

Positive Samples: A-549, U-87MG, HeLa, Mouse lung, Rat lung

Immunogen sequence: VGTPEVLRVY IGSFWSQPLL VPDNRRLFEL EEQDLFRDIQ GLPRHAALRK LNDLVKRARL VRVHAYIISY LKKEMPSVFG KENKKKQLIL KLPVIFAKIQ LEHHISPGDF PDCQKMQELL MAHDFTKFHS LKPKLLEALD EMLTHDIAKL MPLLRQEELE STEVGVQGGA FEGTHMGPFV ERGPDEAMED GEEGSDDEAE WVVTKDKSKY DEIFYNLAPA DGKLSGSKAK TWMVGTKLPN SVLGRIWKLS DVDRDGMLDD EEFALASHLI EAKLEGHGLP ANLPRRLVPP SKRRHKGSAE

Target Information

This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.