Thermo Fisher Scientific PEG3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 195-400 of human PEG3 (NP_0062011) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PEG3,uniProtId:Q9GZU2-1,ncbiNodeId:9606,antigenRange:195-400,antigenLength:1588,antigenImageFileName:PA5-116550_PEG3_Q9GZU2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116550_PEG3_Q9GZU2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901181

Product Specific Information

Positive Samples: HepG2

Immunogen sequence: LSLPVVAKTS FEMDREDDRD SRAYESRSQD AESYQNVVDL AEDRKPHNTI QDNMENYRKL LSLVQLAEDD GHSHMTQGHS SRSKRSAYPS TSRGLKTMPE AKKSTHRRGI CEDESSHGVI MEKFIKDVSR SSKSGRARES SDRSQRFPRM SDDNWKDISL NKRESVIQQR VYEGNAFRGG FRFNSTLVSR KRVLERKRRY HFDTDG

Target Information

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5exons and a common promoter and both genes are paternally expressed. Alternative splicing events connect their shared 5 exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.