Thermo Fisher Scientific PEG3 Polyclonal Antibody
Thermo Fisher Scientific의 PEG3 폴리클로날 항체는 인간, 생쥐, 랫트 시료에 반응하며 Western blot, IHC, ELISA 등에 적합합니다. HepG2 세포에서 양성 반응을 보이며, 세포 증식 및 종양 억제 관련 연구에 활용됩니다. 액상 형태로 -20°C 보관이 권장됩니다.
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Thermo Fisher Scientific PEG3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 195–400 of human PEG3 (NP_006201.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901181 |
Product Specific Information
- Positive Samples: HepG2
- Immunogen Sequence:
LSLPVVAKTS FEMDREDDRD SRAYESRSQD AESYQNVVDL AEDRKPHNTI QDNMENYRKL LSLVQLAEDD GHSHMTQGHS SRSKRSAYPS TSRGLKTMPE AKKSTHRRGI CEDESSHGVI MEKFIKDVSR SSKSGRARES SDRSQRFPRM SDDNWKDISL NKRESVIQQR VYEGNAFRGG FRFNSTLVSR KRVLERKRRY HFDTDG
Target Information
In humans, ZIM2 and PEG3 are distinct genes sharing multiple 5′ exons and a common promoter, both paternally expressed. Alternative splicing connects shared exons to unique exons of ZIM2 or PEG3. In other mammals, ZIM2 is not imprinted and does not share exons with PEG3. Human PEG3 belongs to the Kruppel C2H2-type zinc finger protein family, playing roles in cell proliferation and p53-mediated apoptosis. PEG3 exhibits tumor suppressor activity and involvement in tumorigenesis in glioma and ovarian cells. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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