Thermo Fisher Scientific ARSG Monoclonal Antibody (OTI2D12), TrueMAB
ARSG 단백질을 인식하는 Mouse monoclonal antibody로 Western Blot에 적합. Human 시료에 반응하며, 동결건조 형태로 제공. PBS 버퍼(pH 7.3, 8% trehalose) 내 보존, -20°C 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 17–525 of human ARSG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Sulfatases such as ARSG hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They play roles in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules.
ARSG is a novel arylsulfatase with activity toward pseudosubstrates including p-nitrocatechol sulfate and 4-methylumbelliferyl sulfate, competitively inhibited by phosphate.
The unprocessed protein functions as a 63-kDa monomer with an acidic pH optimum typical of lysosomal sulfatases. It accumulates within lysosomes and is a glycoprotein that binds specifically to mannose 6-phosphate receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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