Thermo Fisher Scientific RNF12 Polyclonal Antibody
RNF12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 고순도 Affinity Chromatography로 정제됨. Human RNF12 C-terminal 펩타이드(aa 532–581)를 면역원으로 사용. 연구용 전용 제품.
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Thermo Fisher Scientific RNF12 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human RNF12 (aa 532–581) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576966 |
Product Specific Information
- Peptide sequence: AQFFLLNEDD DDQPRGLTKE QIDNLAMRSF GENDALKTCS VCITEYTEGN
- Sequence homology:
Cow: 100% / Dog: 100% / Guinea Pig: 93% / Horse: 100% / Human: 100% / Mouse: 93% / Pig: 100% / Rabbit: 100% / Rat: 93% / Yeast: 89% / Zebrafish: 93%
Target Information
RNF12 is a RING-H2 zinc finger protein functioning as a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), leading to proteasome-dependent degradation of LDB1. RNF12 and LDB1 act as co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-40489_RNF12_Q9NVW2-1_Rabbit.svg, PA5-40489_RNF12_Q9NVW2-1_Rabbit_PDP.jpeg)
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