Thermo Fisher Scientific IQGAP1 Monoclonal Antibody (OTI6E1), TrueMAB
IQGAP1 단백질을 인식하는 Mouse monoclonal 항체로, WB와 IHC(P)에서 검증됨. Human, Mouse, Rat에 반응하며, carrier-free 형태로 제공. 세포 형태 및 이동 조절 관련 연구에 적합. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 464–609 of human IQGAP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The IQGAP1 gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain, and one WW domain. It interacts with cytoskeletal components, cell adhesion molecules, and signaling molecules to regulate cell morphology and motility. Expression of this protein is upregulated by gene amplification in certain gastric cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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