Thermo Fisher Scientific Human IL-6, Animal-Free Recombinant Protein, PeproTech
인간 IL-6 재조합 단백질로, E. coli 발현 시스템에서 생산된 동물 유래 성분 없는 고순도 단백질입니다. 염증 반응 및 B세포 성숙 관련 연구에 적합하며, ≥98% 순도와 낮은 엔도톡신 수준을 보장합니다. 실온 배송 및 -20°C 보관 권장.
- 카탈로그번호
- AF-200-06-xxxxx (3개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human IL-6, Animal-Free Recombinant Protein, PeproTech
Applications
ELISA
- Tested Dilution: Not specified
- Publications: View 1 publication
Functional Assay
- Assay-dependent
- Publications: View references
In vitro Assay
- Tested Dilution: Not specified
- Publications: View 62 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM |
| Molecular Weight | 20.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | Stimulates proliferation of mouse B9 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin-6 (IL-6) encodes a cytokine involved in inflammation and B cell maturation.
The protein acts as an endogenous pyrogen, inducing fever in autoimmune or infectious conditions.
It is primarily expressed at sites of acute and chronic inflammation, secreted into serum, and triggers a transcriptional inflammatory response via the interleukin 6 receptor (IL-6Rα).
IL-6 function is implicated in various inflammation-related diseases such as diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and rheumatoid arthritis.
Elevated IL-6 levels have also been observed in viral infections, including COVID-19 (SARS-CoV-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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