Thermo Fisher Scientific RNF6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RNF6. Recombinant protein control fragment (Product #RP-102869). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RNF6,uniProtId:Q9Y252-1,ncbiNodeId:9606,antigenRange:319-393,antigenLength:685,antigenImageFileName:PA5-58746_RNF6_Q9Y252-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58746_RNF6_Q9Y252-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646682

Product Specific Information

Immunogen sequence: SGTVYHNSQR ESRPVQQTTR RSVRRRGRTR VFLEQDRERE RRGTAYTPFS NSRLVSRITV EEGEESSRSS TAVRR

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 72%.

Target Information

The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.