Thermo Fisher Scientific SPTY2D1 Polyclonal Antibody
SPTY2D1 단백질을 인식하는 Rabbit Polyclonal 항체. 인체 시료에 반응하며 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 장기 보관 시 -20°C에서 안정적 유지.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SPTY2D1. Recombinant protein control fragment (Product #RP-97507). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647902 |
Product Specific Information
- Immunogen sequence:
PPPMNFTDLL RLAEKKQFEP VEIKVVKKSE ERPMTAEELR EREFLERKHR RKKLETDGKL PPTVSKKAPS QKESVGTK - Antigen sequence identity:
Mouse - 82%, Rat - 79%
Target Information
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). Binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). Modulates RNA polymerase 1-mediated transcription. Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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