Thermo Fisher Scientific Phospho-Rb (Ser807, Ser811) Recombinant Rabbit Monoclonal Antibody (RbS807S811-D9), APC
APC 형광 표지된 재조합 Rabbit Monoclonal 항체로, 인산화된 Rb(Ser807/811)를 검출. 인간 및 마우스 시료에 반응하며 Flow Cytometry에 적합. Protein A/G 정제, PBS+BSA buffer, 4°C 보관.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RbS807S811-D9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser807/811 of human phospho-Rb |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897180 |
Additional Formats
Target Information
Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues, but not on tyrosine. It forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription, and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene are implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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