Thermo Fisher Scientific Phospho-ATF2 (Thr71) Recombinant Rabbit Monoclonal Antibody (ATF2T71-G3), PE
PE 형광 표지된 재조합 Rabbit Monoclonal 항체로 ATF2의 Thr71 인산화 형태를 검출. 인간 및 마우스 시료에 반응하며 Flow Cytometry에 적합. HEK293 발현 시스템 기반, Protein A/G 정제, PBS+BSA 버퍼 저장.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ATF2T71-G3 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr71 of human phospho ATF2 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897181 |
Additional Formats
Target Information
The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins.
ATF-2 interacts with viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways.
Cellular stress such as genotoxic agents, inflammatory cytokines, and UV irradiation activates ATF-2 transcriptional activity by phosphorylation at Thr69 and Thr71.
Both SAPK and p38 MAPK phosphorylate ATF-2 at these sites in vitro and in transfected cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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