Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
Human TRAF3IP1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 저장. 세포 신호전달 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRAF3IP1. Recombinant protein control fragment (Product # RP-96238) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648870 |
Product Specific Information
Immunogen sequence:
IGKCCLNKLS SDDAVRRVLA GEKGEVKGRA SLTSRSQELD NKNVREEESR VHKNTEDRGD AEIKERSTSR DRKQKEELKE DR
Highest antigen sequence identity to the following orthologs:
- Mouse: 65%
- Rat: 65%
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation, and apoptosis in various cell types. TNFR-associated factors (TRAFs) are a family of proteins initially discovered as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region essential for downstream signaling. MIP-T3 (TRAF3IP1) associates with TRAF3, binds to taxol-stabilized microtubules and tubulin in vitro, and recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3, suggesting a mechanism for sequestering TRAF3 to the cytoskeletal network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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