Thermo Fisher Scientific MMP7 Monoclonal Antibody (OTI2E1), TrueMAB

Thermo Fisher Scientific MMP7 Monoclonal Antibody (OTI2E1), TrueMAB

Applications

• Western Blot (WB)
  Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)

Target Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, and in disease processes such as arthritis and metastasis.
Most MMPs are secreted as inactive proproteins that are activated by cleavage via extracellular proteinases.
The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin, and casein, and differs from most MMP family members by lacking a conserved C-terminal protein domain.
It plays roles in wound healing and regulation of defensin activity in intestinal mucosa.
The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.