Thermo Fisher Scientific SOX21 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Immunocytochemistry (ICC/IF)

5-15 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived recombinant human SOX21 Ser2-Leu276 (Gly102Ser) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SOX21,uniProtId:Q9Y651-1,ncbiNodeId:9606,antigenRange:2-276,antigenLength:276,antigenImageFileName:PA5-47505_SOX21_Q9Y651-1_Goat.svg,antigenImageFileNamePDP:PA5-47505_SOX21_Q9Y651-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2576288

Product Specific Information

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) SOX1, rhSOX2 and rhSOX15 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

The SOX gene family is defined by the Sry-related HMG box domain that mediates sequence-specific DNA binding. A variety of functions are associated with the SOX proteins during development. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. SOX21 may play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can cause an up-regulation of the OPRM1 distal promoter in mor-expressing neuronal cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.