Thermo Fisher Scientific FBLN1 Monoclonal Antibody (3E4)
Human FBLN1 단백질을 인식하는 Mouse monoclonal antibody (Clone 3E4). Western blot 및 ELISA에 최적화. Affinity chromatography로 정제된 액상 형태, PBS buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E4 |
| Immunogen | FBLN1 (AAH22497, 151–250 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF RCQRDSSCGT
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood. It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions may explain its association with basement membranes, connective tissue, elastic fibers, and fibrin clots.
Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies suggest that Fibulin-1 exposure inhibits cancer cell motility. The exact cellular function of Fibulin-1 remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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