Thermo Fisher Scientific FBLN1 Monoclonal Antibody (4C9)
Fibulin-1 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot, ELISA, Immunoprecipitation에 사용 가능. Human 시료 반응성. PBS 기반 액상 형태로 보존제 없음. 연구용으로만 사용.
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Thermo Fisher Scientific FBLN1 Monoclonal Antibody (4C9)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C9 |
| Immunogen | FBLN1 (AAH22497, 151–250 a.a.) partial recombinant protein with GST tag (MW of GST tag = 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GDLDVGGLQE TDKIIEVEEE QEDPYLNDRC RGGGPCKQQC RDTGDEVVCS CFVGYQLLSD GVSCEDVNEC ITGSHSCRLG ESCINTVGSF RCQRDSSCGT
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood.
It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions may explain its association with basement membranes, connective tissue, elastic fibers, and fibrin clots.
Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and may serve as an indicator for cancer risk or aggressiveness. It may also inhibit cancer cell motility with increasing exposure.
The exact function of Fibulin-1 in the cell remains unknown.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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