Thermo Fisher Scientific TRAC-1 Polyclonal Antibody
TRAC-1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 1 mg/mL 농도의 액상형 제품입니다. RNF125 유래 펩타이드를 면역원으로 사용하였으며, 친화 크로마토그래피로 정제되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RNF125 (Accession Q96EQ8), corresponding to amino acid residues R138–L188. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2854326 |
Product Specific Information
This antibody detects endogenous levels of total RNF125.
Target Information
TRAC-1 is a 232 amino acid protein containing an N-terminal RING-type zinc finger domain. It functions as a positive regulator in the T-cell receptor signaling pathway, leading to T-cell activation. It mediates ubiquitination and subsequent proteasomal degradation of target proteins. TRAC-1 is expressed in lymphoid tissues including bone marrow, spleen, and thymus, as well as in other tissues. It is predominantly expressed in CD4+ and CD8+ T-cells, suggesting preferential confinement to T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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