Thermo Fisher Scientific WDR20 Polyclonal Antibody
Thermo Fisher Scientific의 WDR20 Polyclonal Antibody는 인간 WDR20 단백질(450–500번 잔기 영역)에 특이적으로 반응하는 토끼 IgG 항체입니다. IHC 및 IHC(P) 실험에 적합하며, 다양한 종에서 교차 반응이 예측됩니다. 항원 친화 크로마토그래피로 정제된 액상 형태로 제공됩니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of Human WD repeat domain 20 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Turkey, Rabbit, Orangutan, Monkey, Gorilla, Chimpanzee, Japanese pufferfish, and Chinese hamster.
Target Information
CUL-2 is a member of the family of human cullin genes (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene. CUL-1 forms a complex with human p19skp1 and F box protein p45skp2. Together with cdc53 (known as CulA), these three subunits form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins.
In contrast to CUL-1, CUL-2 does not associate with p19skp1 and p45skp2. Instead, CUL-2 forms a complex with an inactive transcriptional elongation complex, SIII, composed of Elongin C, Elongin B, and VHL. The function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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