Thermo Fisher Scientific B-Myb Polyclonal Antibody
B-Myb 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 IHC(P) 실험에 적합합니다. Antigen affinity chromatography로 정제되었으며, Human을 포함한 다양한 종에 반응 예측됩니다. 액상 형태, 4°C 보관, 연구용 전용 제품입니다.
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Thermo Fisher Scientific B-Myb Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of human MYB-related protein B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Bovine, Dog, Horse, Rabbit, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, and Crab-eating macaque
Target Information
Nucleocytoplasmic transport is a signal- and energy-dependent process occurring through nuclear pore complexes embedded in the nuclear envelope. Proteins containing a nuclear localization signal (NLS) are imported via importin alpha and beta subunits (karyopherins). Importin alpha binds NLS-containing cargo in the cytoplasm, and importin beta docks the complex at the nuclear pore. In the presence of nucleoside triphosphates and Ran GTPase, the complex translocates into the nucleus, where importin subunits dissociate. Importin alpha enters the nucleoplasm with its cargo, while importin beta remains at the pore. Interactions between importin beta and FG repeats of nucleoporins are essential for translocation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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