Thermo Fisher Scientific AKAP10 Polyclonal Antibody
AKAP10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA585225
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific AKAP10 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
- Immunocytochemistry (ICC/IF): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AKAP10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792368 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: Synthetic peptide (1:8,000).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
A-kinase anchor proteins (AKAPs) are structurally diverse proteins that bind to the regulatory subunit of protein kinase A (PKA) and localize the holoenzyme to specific cellular compartments.
AKAP10 interacts with both type I and type II regulatory subunits of PKA, functioning as a dual-specific AKAP. It is highly enriched in mitochondria and contains RGS domains in addition to a PKA-RII subunit-binding domain. These features suggest roles in PKA and G protein signal transduction.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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