Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI1A9), TrueMAB

Thermo Fisher Scientific NR2C1 Monoclonal Antibody (OTI1A9), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a nuclear hormone receptor characterized by:

• A highly conserved DNA binding domain (DBD)
• A variable hinge region
• A carboxy-terminal ligand binding domain (LBD)

These features are typical for all members of the steroid/thyroid hormone receptor superfamily.
The protein functions as a ligand-inducible transcription factor regulating gene expression by binding to promoter DNA sequences of target genes.
Multiple alternatively spliced transcript variants have been described, though some full-length forms remain undetermined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.