Thermo Fisher Scientific GBA Monoclonal Antibody (OTI2B2), TrueMAB
GBA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 GBA(aa 40–315) 재조합 단백질을 면역원으로 제작되었으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 40–315 of human GBA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The GBA gene encodes a lysosomal membrane protein that hydrolyzes the β-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism.
Mutations in GBA cause Gaucher disease, a lysosomal storage disorder characterized by accumulation of glucocerebrosides.
A related pseudogene is located approximately 12 kb downstream on chromosome 1.
Alternative splicing results in multiple transcript variants.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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