Thermo Fisher Scientific JAB1 Recombinant Rabbit Monoclonal Antibody (ARC0895)
JAB1 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF, ELISA, ChIP 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 안정적인 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| ChIP assay (ChIP) | 5 µg antibody for 10–15 µg of Chromatin |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0895 |
| Immunogen | Recombinant fusion protein containing amino acids 1–100 of human JAB1/CSN5/COPS5 (Q92905) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849340 |
Product Specific Information
Immunogen sequence:
MAASGSGMAQ KTWELANNMQ EAQSIDEIYK YDKKQQQEIL AAKPWTKDHH YFKYCKISAL ALLKMVMHAR SGGNLEVMGL MLGKVDGETM IIMDSFALPV
Target Information
JAB-1 is a 38 kDa protein originally described as a coactivator for cJUN. It is part of a large protein complex called the Signalosome, proposed to play a signaling role in mammalian cells. This complex is analogous to the COP9 complex in plants, which is important in light-mediated development. Although the specific function of JAB-1 is unclear, it has been implicated in targeting proteins for proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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