Thermo Fisher Scientific CXCR6 Monoclonal Antibody (2A4D10)
CXCR6 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, Flow cytometry, ELISA 등에 사용 가능. 인간 시료 반응성, Protein G 정제, 액상 형태로 제공. HIV/SIV 수용체 연구 및 NKT 세포 표지에 활용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A4D10 |
| Immunogen | Purified recombinant fragment of human CD186 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at −20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090919 |
Target Information
CD186, also known as CXCR6, is a G protein–coupled chemokine receptor that serves as one of the cellular receptors for HIV and SIV. CD186 is expressed by NKT cells, various activated and memory T-cell subsets, and some plasma cells. In mice, liver NK cells—but not naïve or splenic NK cells—express CD186. Its ligand, CXCL16, is expressed by macrophages, dendritic cells, and liver endothelial cells. Due to its high expression on NKT cells, CD186 is often used as a proxy marker for this cell subset.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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