Thermo Fisher Scientific AGR2 Monoclonal Antibody (7H2H7)
AGR2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry, ELISA 등에 사용 가능. 인간 시료 반응성, Protein G 정제, PBS buffer 및 sodium azide 포함. 암 연구 및 표적 단백질 분석에 적합.
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Thermo Fisher Scientific AGR2 Monoclonal Antibody (7H2H7)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H2H7 |
| Immunogen | Purified recombinant fragment of human AGR2 (AA: 21–175) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091024 |
Target Information
AGR2 (anterior gradient protein 2) and AGR3 are members of the anterior gradient homolog family. They are secreted cytoplasmic proteins involved in metastasis induction and p53 tumor suppressor inhibition. AGR2 may serve as a molecular marker and potential therapeutic target for hormone-responsive breast tumors.
AGR2 is ubiquitously expressed and upregulated in prostate, breast, lung, renal, and endometrial carcinomas. Its expression is positively correlated with estrogen receptor (ER) and negatively correlated with epidermal growth factor receptor (EGFR).
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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