Thermo Fisher Scientific ELG-1 Polyclonal Antibody
Human ELG-1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, ELISA, Immunoprecipitation에 사용 가능. Affinity chromatography로 정제된 액상형 항체이며, DNA 손상 반응 연구에 적합. -20°C 보관, 반복적인 동결/해동은 피해야 함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:3,000–1:15,000 |
| Immunoprecipitation (IP) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from whole rabbit serum immunized with a synthetic peptide corresponding to amino acids 63–76 of Human Elg1 (ATAD5, UniProt ID: Q96QE3-1, NCBI Node ID: 9606, antigen range: 63–76). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C prior to opening.
- Aliquot contents and freeze at -20°C or below for extended storage.
- Avoid freeze/thaw cycles.
- Centrifuge if not clear after standing at room temperature.
- Stable for several weeks at 4°C as undiluted liquid.
- Dilute only prior to immediate use.
This affinity purified antibody is directed against human Elg1 protein.
BLAST analysis suggests full to partial reactivity with several hypothetical proteins.
Highly homologous proteins include:
- Human chromosome fragility associated gene 1 (NP_079133)
- Hypothetical dog protein FLJ12735 (XP_548276)
- Hypothetical chimpanzee protein FLJ12735 (XP_511388)
- Hypothetical human protein of 1224 residues (CAH10412)
All show 100% homology to the immunogen.
Reactivity against homologues from other sources is not known.
Target Information
Involved in DNA damage response.
Participates in a RAD9A-related damage checkpoint pathway, determining whether DNA damage is compatible with cell survival or requires apoptosis.
Modulates RAD9A interaction with BCL2 and induces DNA damage–induced apoptosis.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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