Thermo Fisher Scientific HALLEN Polyclonal Antibody
Human Hallen 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, ELISA, Immunoprecipitation 등에 사용 가능. Affinity chromatography로 정제된 액상 시약이며, -20°C 보관 권장. DNA 손상 복구 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500 – 1:2,000
ELISA
- Tested Dilution: 1:10,000 – 1:50,000
Immunoprecipitation (IP)
- Tested Dilution: 1:500 – 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity purified antibody prepared from rabbit serum immunized with synthetic peptide (amino acids 75–100 of Human Hallen). Hallen is a novel BRCT domain-containing protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate (pH 7.2), 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Target Information
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and maintaining genomic stability (PubMed:25931565).
The SLF1-SLF2 complex links RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand break (DSB) sites during DNA repair in response to stalled replication forks (PubMed:25931565).
Promotes recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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