Thermo Fisher Scientific LCAT Recombinant Rabbit Monoclonal Antibody (ARC2383)
LCAT 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 생쥐, 랫트 반응성 보유. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 PBS/glycerol buffer에 보존됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC2383 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human LCAT (P04180) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897786 |
Product Specific Information
- Positive Samples: Mouse plasma, Rat plasma
- Immunogen sequence:
MGPPGSPWQW VTLLLGLLLP PAAPFWLLNV LFPPHTTPKA ELSNHTRPVI LVPGCLGNQL EAKLDKPDVV NWMCYRKTED FFTIWLDLNM FLPLGVDCWI
Target Information
Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP), it also contributes to VLDL and LDL cholesteryl ester formation.
LCAT facilitates reverse cholesterol transport by esterifying cholesterol, enabling its movement from peripheral tissues to the liver for excretion.
Deficiency leads to low plasma HDL, while overexpression increases plasma HDL levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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