Thermo Fisher Scientific SGK1 Polyclonal Antibody
SGK1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. 고순도 항원 친화 크로마토그래피 정제. 인간, 마우스, 랫트 반응성. 연구용으로 세포 스트레스 및 생존 관련 신호 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- View 2 publications
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
- View publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the carboxy terminus of human SGK1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11151949 |
Product Specific Information
- Suggested positive control: human stomach tissue lysate
- PA5-21147 can be used with blocking peptide PEP-1261.
Target Information
SGK (SGK1) is a serine/threonine kinase that may be a transcriptional target for p38/MAPK in hepatoma cells.
SGK plays an important role in cellular stress response and cell survival.
SGK1 is transcriptionally activated by numerous stimuli, including serum, glucocorticoids, osmotic stress, and hormones.
It phosphorylates and negatively regulates pro-apoptotic FOXO3A.
SGK1 is thought to play an essential function in nephropathy and cardiovascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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