Thermo Fisher Scientific Thymidine Phosphorylase Monoclonal Antibody (P-GF.44C)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-3 µg/mL

-

Immunohistochemistry (IHC)

-

View 14 publications 14 publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

View 3 publications 3 publications

ELISA (ELISA)

-

View 3 publications 3 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

P-GF.44C

Immunogen

Recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thymidine Phosphorylase,uniProtId:P19971-1,ncbiNodeId:9606,antigenRange:1-482,antigenLength:482,antigenImageFileName:MA5-13542_Thymidine_Phosphorylase_P19971-1_House_mouse.svg,antigenImageFileNamePDP:MA5-13542_Thymidine_Phosphorylase_P19971-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 0.2% BSA

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10985215

Product Specific Information

MA5-13542 targets Thymidine Phosphorylase in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.

The MA5-13542 immunogen is recombinant full length human thymidine phosphorylase (TP/PD-ECGF) protein.

Target Information

A platelet-derived endothelial growth factor (PD-ECGF), same as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.