Thermo Fisher Scientific HLA-ABC Monoclonal Antibody (246-B8.E7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:10-1:100

-

Flow Cytometry (Flow)

0.5 µg/test

-

Product Specifications

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

246-B8.E7

Immunogen

Human peripheral blood leukocytes

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10979940

Product Specific Information

MA5-13582 targets Human MHC I (HLA-A B C) in FACS and WB applications and shows reactivity with Human, Mouse and Non-human primate samples.

The MA5-13582 immunogen is human peripheral blood leukocytes.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.