Thermo Fisher Scientific NUP160 Polyclonal Antibody
NUP160 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 1 mg/mL 농도의 액상 제품이며 4°C에서 보관합니다. 핵공복합체 연구 및 HIV 관련 단백질 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
Immunoprecipitation (IP)
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 600–650 of NUP160 (UniProt ID: Q12769-1, Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| Shelf Life | 1 year from date of receipt |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and cytoplasm. The mammalian nucleoporin (NUP)-160 is part of a hetero-oligomeric complex that includes NUP107, NUP133, NUP96, and yeast sec13p homologs.
While most of the NUP107–160 sub-complex localizes to the nuclear pore, a small fraction associates with kinetochores and spindle poles during mitosis, interacting with proteins such as Mad1, Mad2, Bub3, and Cdc20.
Immunodepletion of the NUP107–160 complex leads to defective spindle assembly, indicating multiple cellular roles. NUP160 has also been identified as an HIV dependency factor (HDF), suggesting potential as a drug target in HIV research. Multiple isoforms of NUP160 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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