Thermo Fisher Scientific Phospho-SQSTM1 (Ser28) Polyclonal Antibody
Phospho-SQSTM1(Ser28)을 인식하는 Rabbit Polyclonal Antibody로, Human·Mouse·Rat 시료에 반응합니다. Western blot에 1:500~1:2,000 희석으로 사용 가능하며, PBS/glycerol buffer에 보관됩니다. NF-κB 경로 관련 SQSTM1 연구에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SQSTM1 (Accession Q13501), corresponding to amino acid residues around phosphorylated Ser28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817618 |
Product Specific Information
Antibody detects endogenous levels of SQSTM1/p62 only. Phospho-SQSTM1/p62 (Ser28) Antibody.
Target Information
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-κB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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