Thermo Fisher Scientific Human WDR35 Synthetic Peptide
인간 WDR35 단백질의 N말단 부위를 기반으로 한 합성 펩타이드로, 항체 차단(Blocking) 실험에 사용 가능. WD40 반복 도메인을 연구하는 데 유용하며, 세포 신호전달 및 섬모 형성과 관련된 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 16-amino acid sequence near the amino terminus of human WDR35.
PEP-1413 can be used as a blocking peptide with polyclonal antibody PA5-34370.
Target Information
WD40 repeats are a common structural module in eukaryotic proteins. Proteins containing WD40 domains have diverse functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription.
WDR35 (also known as CED2) mutations are associated with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disorder characterized by craniosynostosis and ectodermal and skeletal abnormalities.
WDR35 localizes to cilia and centrosomes during embryogenesis. Human and mouse fibroblasts lacking this gene fail to produce cilia. Mutations in WDR35 can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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