Thermo Fisher Scientific Human ZNF521 Synthetic Peptide
Human ZNF521 단백질의 C-말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드. 항체 PA5-34373의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. 연구용 전용 시약.
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Thermo Fisher Scientific Human ZNF521 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 19 amino acid sequence near the carboxy terminus of human ZNF521.
PEP-1416 can be used as a blocking peptide with polyclonal antibody PA5-34373.
Target Information
The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors.
ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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