Thermo Fisher Scientific PKA C alpha/beta Polyclonal Antibody
PKA α/β 단백질의 내인성 수준을 검출하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. 고순도 친화 크로마토그래피 정제, PBS+50% glycerol 보존. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PRKACA (Accession P17612), corresponding to amino acid residues M1–I47 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900398 |
Product Specific Information
Antibody detects endogenous levels of total PKA alpha/beta CAT.
Target Information
cAMP is a signaling molecule important for a variety of cellular functions. It activates cAMP-dependent protein kinase (AMPK), which transduces signals through phosphorylation of target proteins. The inactive holoenzyme of AMPK consists of two regulatory and two catalytic subunits. Upon cAMP binding, the holoenzyme dissociates into regulatory dimers and free catalytic monomers. In humans, four regulatory and three catalytic subunits of AMPK have been identified. PRKACB belongs to the Ser/Thr protein kinase family and functions as a catalytic subunit of AMPK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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