Thermo Fisher Scientific PKC mu Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Immunohistochemistry (PFA fixed) (IHC (PFA))
1:50-1:200
Immunocytochemistry (ICC/IF)
1:100-1:500
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRKD1(Accession Q15139), corresponding to amino acid residues R439-P489. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PKC mu,
uniProtId:
Q15139-1,
ncbiNodeId:
9606,
antigenRange:
439-489,
antigenLength:
912,
antigenImageFileName:
PA5-115765_PKC_mu_Q15139-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-115765_PKC_mu_Q15139-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900400
Product Specific Information
Antibody detects endogenous levels of total PKD1/PKC mu.
Target Information
The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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