Thermo Fisher Scientific CKMT1A Polyclonal Antibody
Rabbit 유래 다클론 항체로, CKMT1A 단백질을 검출하는 데 사용됩니다. Western blot 및 Immunoprecipitation에 적합하며, 직접 ELISA에도 활용 가능합니다. 고순도 액상 형태로 제공되며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5112146
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CKMT1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2866882 |
Product Specific Information
This product can be used in direct ELISA.
Target Information
Mitochondrial creatine kinase (MtCK) is responsible for transferring high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes: sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two oligomeric forms—dimers and octamers—unlike the exclusively dimeric cytosolic isoenzymes. Overexpression of ubiquitous mitochondrial creatine kinase has been associated with malignant cancers exhibiting poor prognosis, possibly due to high energy turnover and reduced apoptosis. Ubiquitous mitochondrial creatine kinase shares approximately 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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