Thermo Fisher Scientific NAE1 Monoclonal Antibody (OTI1B2), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The NAE1 gene encodes a protein that binds to the beta-amyloid precursor protein, which is implicated in the pathogenesis of Alzheimer’s disease.
NAE1 forms a heterodimer with UBE1C to bind and activate NEDD8, a ubiquitin-like protein essential for cell cycle progression through the S/M checkpoint.
Three transcript variants encoding different isoforms have been identified for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.