Thermo Fisher Scientific ESRRA Polyclonal Antibody
ESRRA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP, ChIP 등 다양한 응용에 적합. 인간 반응성, 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C에서 안정적 유지.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunoprecipitation (IP) | 1:100–1:500 | - |
| ChIP assay (ChIP) | Assay-dependent | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 69–359 of Human ERR alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.93 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545866 |
Product Specific Information
- Recommended positive controls: 293T
- Predicted reactivity: Mouse (98%), Rat (98%), Dog (98%), Pig (99%), Bovine (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Estrogen-related receptor alpha 1 (ERRα, ERR1) is an orphan member of the nuclear hormone receptor superfamily. The ERR family shares an almost identical DNA-binding domain, having 68% amino acid identity with the estrogen receptor. ERRα binds to an ERR-alpha response element (ERRE) containing a single consensus half-site (5’-tnaaggtca-3’) and can also bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1, acting as a regulator of the MCAD promoter. Studies show ERR1 functions as a metabolic regulator and is expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for ERR1 is NR3B1.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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