Thermo Fisher Scientific RET Monoclonal Antibody (OTI5D4), TrueMAB
RET 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot과 파라핀 IHC에 적합합니다. 인간 RET(aa 713-1017) 재조합 단백질을 면역원으로 제작되었으며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific RET Monoclonal Antibody (OTI5D4), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 713–1017 of human RET produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step. (Recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)
Target Information
RET is a receptor tyrosine kinase belonging to the cadherin superfamily. It plays a key role in neural crest development and can become oncogenically activated through cytogenetic rearrangement. RET mediates cell growth and differentiation signals.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Two transcript variants encoding different isoforms have been identified, with additional variants described but not biologically validated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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