Thermo Fisher Scientific HTR3A Polyclonal Antibody
HTR3A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 시료 반응성. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HTR3A (Accession P46098), corresponding to amino acid residues S370–Q420 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850423 |
Product Specific Information
This antibody detects endogenous levels of total 5HT3A receptor.
Target Information
The HTR3A gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), which belongs to the ligand-gated ion channel receptor superfamily. This receptor mediates fast, depolarizing responses in neurons upon activation. Functional receptor activity typically requires heteromeric assembly of A and B subunits; single subunits alone exhibit low conductance and response amplitude. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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