
Thermo Fisher Scientific NDUFA13 Polyclonal Antibody
Thermo Fisher Scientific의 NDUFA13 다클론 항체는 인간 단백질을 인식하며 Western blot, IHC, IP에 적합합니다. E. coli 유래 항원을 사용해 제작되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human NDUFA13/GRIM 19 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2867013 |
Target Information
A novel gene associated with Retinoid-IFN-induced Mortality (GRIM), GRIM-19 gene was identified. Antisense expression of GRIM-19 confers strong resistance against IFN/RA-induced death by reducing intracellular levels of GRIM-19 protein. Overexpression of GRIM-19 enhances cell death in response to IFN/RA. GRIM-19 is primarily a nuclear protein whose expression is induced by the IFN/RA combination. These data indicate that GRIM-19 is a novel cell death-regulatory molecule.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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