Thermo Fisher Scientific NDUFS2 Polyclonal Antibody
Rabbit polyclonal antibody against human NDUFS2 protein. Validated for WB, IHC (Paraffin), and IP applications. Suitable for mitochondrial complex I research. Supplied as liquid, 1 mg/mL, stored at 4°C or -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1–5 µL/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human NDUFS2 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2867014 |
Target Information
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Mammalian mitochondrial complex I consists of at least 43 subunits—7 encoded by the mitochondrial genome and the remainder by nuclear genes. The iron-sulfur protein fraction includes 7 subunits, including this gene product. Complex I catalyzes NADH oxidation with concomitant ubiquinone reduction and proton ejection from mitochondria. Mutations in this gene are linked to mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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