Thermo Fisher Scientific PCCA Polyclonal Antibody
Thermo Fisher Scientific의 PCCA 폴리클로날 항체는 인간, 마우스, 랫트에 반응하며 Western Blot 및 IHC(파라핀) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도이며 장기 보관 시 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 482–716 of Human PCCA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547591 |
Product Specific Information
- Recommended positive controls: HeLa
- Predicted reactivity: Mouse (86%), Rat (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine.
It is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits.
The protein is located in the mitochondrial matrix.
Defects in PCCA are the cause of propionic acidemia type I (PA-1), a life-threatening disease characterized by episodic vomiting, lethargy, ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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