Thermo Fisher Scientific EBP1 Polyclonal Antibody
EBP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunocytochemistry에 사용 가능. 인간과 생쥐에 반응하며 항원 친화 크로마토그래피로 정제됨. 성장 조절 및 리보솜 조립 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 134–346 of Human EBP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.55 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547588 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain
- Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (97%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes an RNA-binding protein involved in growth regulation. It is present in pre-ribosomal ribonucleoprotein complexes and may play a role in ribosome assembly and rRNA processing.
The protein interacts with the cytoplasmic domain of the ErbB3 receptor, contributing to growth regulatory signal transduction. It also functions as a transcriptional co-repressor of androgen receptor-regulated and other cell cycle genes via histone deacetylase interactions.
EBP1 is implicated in growth inhibition and differentiation induction of human cancer cells. Six pseudogenes have been identified on chromosomes 3, 6, 9, 18, 20, and X.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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