Thermo Fisher Scientific GREM1 Monoclonal Antibody (C1)
GREM1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Protein A/G로 정제된 액상 형태이며, PBS+50% glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–30 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C1 |
| Immunogen | Lys26–Asp184 (Accession O60565), with N-terminal His Tag |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2912722 |
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants. The human homolog of Drm/Gremlin (CKTFS1B1) is localized on chromosome 15q13–q15. DRM-specific mRNA is expressed in various human tissues, including brain, ovary, intestine, and colon. Down-regulation of DRM may be associated with tumor progression, suggesting that human DRM plays an important role in neuroembryological development and carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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