
Thermo Fisher Scientific GKN1 Polyclonal Antibody
Thermo Fisher Scientific GKN1 Polyclonal Antibody는 인간 및 다양한 종에서 GKN1 단백질을 검출하는 Rabbit IgG 기반 항체입니다. Western blot에 적합하며, Protein G로 정제된 고순도 제품입니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
- Western Blot (WB): 0.1–0.2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Horse, Human, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Portions of amino acids 100–150 of human GKN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540833 |
Target Information
Gastrokine 1 (GKN1), also known as CA11, is a secreted 185-amino-acid protein of the gastrokine family containing a BRICHOS domain and an asn-rich region. GKN1 functions as an antioncogene and is down-regulated in human gastric cancer tissue compared to normal gastric mucosa. It is predominantly expressed in the stomach, co-secreted with mucins, and acts as a signaling growth factor with mitogenic activity, contributing to the maintenance of gastric mucosal integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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