Thermo Fisher Scientific ANKRD16 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ANKRD16. Recombinant protein control fragment (Product #RP-102793). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ANKRD16,uniProtId:Q6P6B7-1,ncbiNodeId:9606,antigenRange:192-277,antigenLength:361,antigenImageFileName:PA5-58167_ANKRD16_Q6P6B7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58167_ANKRD16_Q6P6B7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637959

Product Specific Information

Immunogen sequence: KRCQYEPDYR DNCGVTALMD AIQCGHIDVA RLLLDEHGAC LSAEDSLGAQ ALHRAAVTGQ DEAIRFLVSE LGVDVDVRAT STHLTA

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.

Target Information

Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.